Blacks hit hard with asthma - why?
I'm always reading new research about asthma. I am so glad I can learn from these smart people!
I just read an article called "Asthma takes a hard toll on African Americans. Can precision medicine ease the burden?"
In the article, they say that "15.3% of black children have asthma, compared to 7.1% of white children........ African American children are also almost 3 times as likely to die from asthma as white people."
A researcher in Boston (Dr. Esteban Burchard) was studying asthma when he said:
“a black teenager died of an asthma attack right outside the hospital entrance. Which is ridiculous. There are 20 hospitals in Boston!”
Now in California, Dr. Burchard and a team of 50 researchers published a paper explaining their findings.
"A set of genetic mutations found mostly in people of African ancestry may make them less likely to respond to albuterol, the most-prescribed asthma drug in the world."
The article mentions other things that contribute to asthma - stress, environmental exposures and even social forces such as racism and poverty.
So, how to find those that are resistant to Albuterol? Researchers are collecting and studying DNA to find those with the NFKB1 gene. That gene is related to smooth muscle response in the lungs. Albuterol usually works by helping to release the constriction of the smooth muscles.
So, my question after reading the article is - if you have the NFKB1 gene, and Albuterol doesn't work, what else is there?
Ipratropium (brand name is Atrovent) could be another option, but it doesn't mention that in the article.
I'm looking forward to learning more from their research!
Comments
Post a Comment